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우수성과SAIHST 구성원의 언론보도내용 및 수상내역, 각 연구분야의 우수 학술지에 게재된 논문 등 우수한 성과들을 소개합니다.

[방창현 교수/ 우수논문] Science Advances , 16 Jun 2021
No -1
작성자 관리자
등록일 2022/10/18

 

 

 

방창현 교수

삼성융합의과학원

 

 IF: 14.972


 

Sci Adv. 2021 Jun 16;7(25):eabf5695. doi: 10.1126/sciadv.abf5695. Print 2021 Jun.

 

Diving beetle-like miniaturized plungers with reversible, rapid biofluid capturing for machine learning-based care of skin disease

 

Sangyul Baik, Jihyun Lee, Eun Je Jeon, Bo-yong Park, Da Wan Kim, Jin Ho Song, Heon Joon Lee, Seung Yeop Han, Seung-Woo Cho, and Changhyun Pang

 

Abstract

Recent advances in bioinspired nano/microstructures have received attention as promising approaches with which to implement smart skin-interfacial devices for personalized health care. In situ skin diagnosis requires adaptable skin adherence and rapid capture of clinical biofluids. Here, we report a simple, all-in-one device consisting of microplungers and hydrogels that can rapidly capture biofluids and conformally attach to skin for stable, real-time monitoring of health. Inspired by the male diving beetle, the microplungers achieve repeatable, enhanced, and multidirectional adhesion to human skin in dry/wet environments, revealing the role of the cavities in these architectures. The hydrogels within the microplungers instantaneously absorb liquids from the epidermis for enhanced adhesiveness and reversibly change color for visual indication of skin pH levels. To realize advanced biomedical technologies for the diagnosis and treatment of skin, our suction-mediated device is integrated with a machine learning framework for accurate and automated colorimetric analysis of pH levels.

 

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