| 이지은 교수 / Ph.D. |
이름 : 이지은 Ph.D.
소속 : 삼성융합의과학원
직급 : 교수
연구실위치 : 서울 강남구 일원로 115 일원역빌딩 C동 4층
E-mail : jieun.lee@skku.edu
Homepage : https://jieunleelab.wixsite.com/mmgl
실험실명 : 분자의학유전체학 연구실
참여학과 : 융합의과학과,디지털헬스학과
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■ Research objective Our lab has been interested in understanding biogenesis of the primary cilium and its role in diverse cellular processes and human diseases. The primary cilium, distinct from the motile cilia, is a cellular organelle that protrudes from the cellular membrane. The primary cilium is non-motile and solely exists in most types of eukaryote cells. Mainly, we identify novel genes from patients or focus on unknown genes to investigate the association of the primary cilium with diseases. Our lab has been also interested in generating disease animal model using zebrafish and applying the models to screening and/or development of therapeutic chemicals. ■ Research interests - Role of the primary cilium in metabolic disorders Our lab currently investigates role of the primary cilium in adipogenesis and the effect of its deficit on metabolic disorders including diabetes and obesity. - Role of the primary cilium in myopathies Our lab currently investigates role of the primary cilium in muscle differentiation and the effect of its deficit on myopathies. - Role of the primary cilium in cancer Our lab currently investigates role of the primary cilium in cell cycle regulation, ubiquitin-proteasome system, and mRNA splicing and the effect of its deficit on cancer. ■ Contact jieun.lee@skku.edu |
